michaela.rumlova@vscht.cz
phone 4177 (220 444 177)
Education
1992 M.S. graduated from UCT Prague, specialization in Enzyme Engineering, diploma thesis: Inhibitors of HIV-1 and HIV-2 proteinases
1996 Ph. D. in Microbiology at UCT Prague: Study and expression of Mason-Pfizer monkey virus proteins
1997-2014 Institute of Organic Chemistry and Biochemistry, Czech Academy of Sciences, v.v.i.
2015 UCT Prague
2019 Associate professor, Department of Biotechnology, UCT Prague
2021 Full professor, Department of Biotechnology, UCT Prague
Experience
Postgraduate courses:
1993: University of Alabama at Birmingham (UAB), USA: Prof. E. Hunter´s laboratory, participation in the project: Study of in vitro assembly of M-PMV Gag polyprotein
1994: UAB, USA: Prof. E. Hunter´s laboratory, participation in the project: M-PMV/HIV chimeric proteins assembly
Postdoctoral fellow:
1996-7: UAB, USA, Prof. E. Hunter´s laboratory, participation in the project: Study of domains critical for HIV-1 and M-PMV assembly
1998: UAB, USA, Prof. E. Hunter´s laboratory, participation in the project: The role CA and NC for the assembly of M-PMV and HIV particles
Major scientific interest:
assembly of retroviral particles, assembly inhibitors screening, structural organization of immature and mature retroviral particles and individual domains, viral host cell protein interactions, SARS-CoV-2 RNA polymerase and its inhibition, flavivirus C protein structural-functional characterization